Endocrine Abstracts

Background: Toxic adenoma (TA) is a rare cause of hyperthyroidism in children, representing less than 3% of cases, more frequently affecting girls. The risk of malignancy in pediatric autonomous nodules is unknown. Despite current guidelines on the management of TA, published case series reveal discrepancies in medical practice.Case presentation: We report a case of TA in a 7-year old boy, incidentally detected as a palpable mass during examination for l...

Objective: Flash Glucose Monitoring (FGM) is becoming increasingly popular among children with Type 1 diabetes. Our aim was to evaluate real-life data from children using FGM followed in our center.Methods: We studied 37 patients (51.4% males), with a mean±S.D. age of 10.1±3.9 years at FGM start for a period of 10.1±6.5 months. HbA1c, BMI z-score, number of self-reported and severe hypoglycemias, total insulin daily dose/kg ...

Aim: To investigate reproductive function disorders in young women with type 1 diabetes mellitus (T1DM).Patients and methods: We studied 53 women with T1DM (duration 8.0±5.6 y) and 51 healthy controls with normal menstrual cycles and no clinical hyperandrogenism, matched for age (19.4±4.3 vs 20.8±3.1 years, P=0.063) and body mass index (BMI) (22.2±2.7 vs 21.4±1.9 kg/m2, P=0.088). T1DM (insulin regimen...